Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model
نویسندگان
چکیده
منابع مشابه
Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model
We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue. After neurologic symptoms appeared, transmissibility of the disease by both inoculation routes was confirmed by detection of disease-associated prion protein in samples of brain tissue.
متن کاملOral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
To determine oral transmissibility of the L-type bovine spongiform encephalopathy (BSE) prion, we orally inoculated 16 calves with brain homogenates of the agent. Only 1 animal, given a high dose, showed signs and died at 88 months. These results suggest low risk for oral transmission of the L-BSE agent among cattle.
متن کاملBovine spongiform encephalopathy.
A detailed account is given of the occurrence of bovine spongiform encephalopathy (BSE), current research into the aetiology of this new disease of cattle, and the relationship between BSE, scrapie and other similar diseases. Epidemiology, clinical signs, pathology, diagnosis, prevention and control are described.
متن کاملBovine Spongiform Encephalopathy
Bovine spongiform encephalopathy (BSE) is a fatal neurodegenerative disease, caused by a prion, that mainly affects cattle. Other ruminant species, cats, non-human primates and humans are occasionally affected; this disease is called feline spongiform encephalopathy (FSE) in cats, and variant Creutzfeldt–Jakob disease (vCJD) in people. BSE is a relatively new disease that was first reported in ...
متن کاملBovine Spongiform Encephalopathy (BSE)
Detailed tables containing information on countries in which BSE has been reported are provided by the World Organisation for Animal Health (OIE) on its website (BSE specific data – www.oie.int). Apart from the 184 169 cases in cattle that were diagnosed in the UK up to the end of 2011, 20 other European countries also recorded the disease, some such as Portugal, Switzerland and Ireland at high...
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 2012
ISSN: 1080-6040,1080-6059
DOI: 10.3201/eid1801.111092